(1) School of Dentistry, University of Queensland, Brisbane, QLD 4000, Australia
(2) UQ Centre for Clinical Research, Royal Brisbane and Women’s Hospital Campus, University of Queensland, Herston, Brisbane, QLD 4029, Australia
* Corresponding author Email: email@example.com
The existence or lack of an association between the use of alcohol-containing mouthwashes and the development of oral squamous cell carcinoma remains a significantly contentious issue within the scientific community. The published literature on the topic includes both epidemiological studies assessing associations on a population level and mechanistic studies investigating the local effects of alcohol-containing mouthwashes in both
While there is a lack of consistent evidence, it is advisable for clinicians to promote the use of non-alcoholic mouthwashes in order to minimise any potential increase in risk, and discourage long-term use of high alcohol-containing products.