(1) Fertility Associates of Memphis, Memphis TN USA
(2) Vanderbilt University School of Medicine, Nashville TN USA
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Preimplantation genetic screening is an increasingly utilized as a tool to optimize the efficiency of IVF in a variety of clinical situations. Initial data from PGS was discouraging using florescence in situ hybridization (FISH) and cleavage stage biopsy. However, more recently the trophectoderm biopsy at the blastocyst stage of embryonic development coupled with evaluation of all 23 chromosome pairs has yielded encouraging clinical results.