For citation purposes: Varras M, Anastasiadis A, Panelos J, Balassi E, Demou A, Akrivis CH. Autoimmune oophoritis: Clinical presentation of an unusual clinical entity. OA Case Reports 2013 Jan 31;2(1):7.

Case report

 
Obstetrics & Gynecology

Autoimmune oophoritis: clinical presentation of an unusual clinical entity

M Varras, A Anastasiadis, J Panelos, E Balassi, A Demou, CH Akrivis
 

Authors affiliations

1 Third Department of Obstetrics and Gynecology, ,‘Elena Venizelou’ General Maternity Hospital, Athens, Greece

2 Fourth Department of Obstetrics and Gynecology, ‘Elena Venizelou’ General Maternity Hospital, Athens, Greece

3 Department of Pathology, ‘G. Chatzikosta’ General State Hospital, Ioannina, Greece

4 Department of Obstetrics and Gynecology, ‘G. Chatzikosta’ General State Hospital, Ioannina, Greece

* Corresponding author Email: mnvarras@otenet.gr

Abstract

Introduction

Autoimmune oophoritis is a rare condition, which provokes ovarian failure with either primary amenorrhea or secondary amenorrhea and a subsequent loss of fertility and ovarian hormonal function. The purpose of this report is to document the clinical findings from two patients with autoimmune oophoritis.

Case report

Two cases of autoimmune oophoritis are presented whose histopathological findings were consistent with international literature. Both cases were histopathologically characterised by lymphocytic and plasmacytic inflammatory infiltrations around the cystic follicles. The inflammation was located both in the theca and granular layers.

Conclusion

Patients with autoimmune oophoritis should be recognised by the histopathology of the ovarian biopsies as they are at an increased risk of developing other autoimmune disorders.

Licensee OA Publishing London 2013. Creative Commons Attribution License (CC-BY)
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