For citation purposes: Petropoulou O, Koumousidis A, Katsetos C, Varras M, Katsoulis M. Pathophysiological and hormonal changes affecting pain during pregnancy: a review. OA Women's Health 2013 Jun 01;1(1):5.

Review

 
Pregnancy

Pathophysiological and hormonal changes affecting pain during pregnancy: a review

O Petropoulou, A Koumousidis, C Katsetos, M Varras, M Katsoulis
 

Authors affiliations

(1) “Tzaneio” General Hospital of Piraeus, Piraeus, Greece

(2) Third Department of Obstetrics and Gynecology “Helena Venizelou” General Hospital – Maternity, Athens, Greece

* Corresponding author E-mail: kumusidi@doctors.org.uk

Abstract

Introduction

There are significant pathophysiological and hormonal changes that take place during pregnancy, which affect almost every system in the body and contribute to successfully overcoming the challenges of pregnancy and labour. The changes noted in the first trimester of pregnancy are mainly of hormonal aetiology, considering the fact that the secretion of progesterone, oestrogens, human chorionic gonadotrophin, prostaglandins and endorphins is significantly increased. The aim of this review is to discuss the pathophysiological and hormonal changes affecting pain during pregnancy.

Conclusion

Pain during pregnancy can become a serious condition, which negatively influences the woman’s quality of life.

Licensee OA Publishing London 2013. Creative Commons Attribution License (CC-BY)
Keywords