For citation purposes: Forbes SH, Ashman N, Yaqoob MM. The role of platelets in the prognosis of renal disease. OA Nephrology 2013 Sep 01;1(2):17.

Critical review

 
Biomedicine

The role of platelets in the prognosis of renal disease

SH Forbes, N Ashman, MM Yaqoob
 

Authors affiliations

Department of Nephrology and Transplantation, Royal London Hospital, Barts Health NHS Trust, Whitechapel, E1 1BB

* Corresponding author Email: Suzanne.Forbes@bartshealth.nhs.uk

Abstract

Introduction

Platelets were first discovered in 1842, identified as ‘little globules’ or ‘granular masses’. Since then, our understanding of these small non-nucleated cells has massively increased, and over the years the humble platelet has been found to be a critical player in many physiological processes. Here, we explore the role of platelets in patients with renal diseases and examine their significance in outcomes.

Conclusion

It is clear that, far from being mere ‘particles in the blood’, platelets are remarkable and exciting cells that have highly evolved and intricate functions spanning far beyond just haemostasis, encompassing many other physiological processes.

Licensee OA Publishing London 2013. Creative Commons Attribution License (CC-BY)