OA Epidemiology

Adherence to the Dutch Guidelines for a Healthy Diet and Cancer Risk in the EPIC-NL Cohort

Proceedings of the 2013 annual meeting of the Netherlands Epidemiology Society

Volume 1 Issue S1 Abstract 48

 

E.A. Struijk, Julius Center, UMC Utrecht; RIVM, Bilthoven, the Netherlands
A.M. May, Julius Center, UMC Utrecht, the Netherlands
J.W.J. Beulens, Julius Center, UMC Utrecht, the Netherlands
H.P. Fransen, Julius Center, UMC Utrecht; RIVM, Bilthoven, the Netherlands
G.A. de Wit, Julius Center, UMC Utrecht; RIVM, Bilthoven, the Netherlands
J.M.A. Boer, RIVM, Bilthoven, the Netherlands
N.C. Onland-Moret, Julius Center, UMC Utrecht, the Netherlands
J. Hoekstra, RIVM, Bilthoven, the Netherlands
Y.T. van der Schouw, Julius Center, UMC Utrecht, the Netherlands
H.B. Bueno-de-Mesquita, RIVM, Bilthoven; UMC Utrecht, the Netherlands
P.H.M. Peeters, Julius Center, UMC Utrecht, the Netherlands

Background
In 2006 the Dutch Health Council published Guidelines for a healthy diet. These guidelines include one recommendation on physical activity and nine recommendations on diet based on the published findings on chronic disease risk. We examined the association between adherence to the guidelines and overall and smoking-related cancer incidence.

Methods
We studied 35,608 men and women aged 20-70 years recruited into the EPIC-NL study during 1993-1997. Adherence to the guidelines was measured using the Dutch Healthy Diet Index (DHD-index) and ranged from 0 to 100 with a higher score indicating greater adherence to the guidelines. We estimated the hazard ratio’s (HRs) and 95% confidence intervals (CI) for the association between the DHD-index (in tertiles and per 20-point increment) and cancer incidence.

Results
After an average follow-up of 12.7 years 3027 cancer cases were documented. We found no significant association between the DHD-index (tertile 3 vs. tertile 1) and overall (HR: 0.97; 95% CI: 0.88-1.07) and smoking-related cancer incidence (HR: 0.89; 95% CI: 0.76-1.06) after adjustment for relevant confounders. Excluding the components physical activity or alcohol from the score did not change the results. None of the individual components of the DHD- index was significantly associated with cancer incidence.

Conclusion
In this study, participants with a high adherence to the Dutch Guidelines for a healthy diet were not at lower risk of overall or smoking-related  cancer. This does not exclude that other components not included in the DHD-index may be associated with overall cancer risk.

Published: 06 Jun, 2013

 
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