OA Epidemiology

Coxiella Burnetii Seroprevalence and Risk Factors in Sheep Farmers and Farm Residents in the Netherlands

Proceedings of the 2013 annual meeting of the Netherlands Epidemiology Society

Volume 1 Issue S1 Abstract 26

 

M.M.A. de Lange, RIVM, Bilthoven, the Netherlands
B. Schimmer, RIVM, Bilthoven, the Netherlands
P. Vellema, Department of Small Ruminant Health, Animal Health Service (GD)
J.L.A. Hautvast, AMPHI, Radboud University, Nijmegen, the Netherlands
P.M. Schneeberger, Jeroen Bosch Hospital, ‘s-Hertogenbosch, the Netherlands
Y.T.H.P. van Duijnhoven, RIVM, Bilthoven, the Netherlands

Background
In this study, Coxiella burnetii seroprevalence was assessed for dairy and non-dairy sheep farm residents in the Netherlands in 2009/2010. Risk factors for seropositivity were identified for non-dairy sheep farm residents.

Methods
Participants filled out farm-based and individual questionnaires. In addition, participants were tested for IgG and IgM Coxiella burnetii antibodies using immunofluorescent assay. Risk factors were identified by univariate, multivariate logistic regression, and multivariate multilevel analyses.

Results
In dairy and non-dairy sheep farm residents, the seroprevalence was 66.7% and 51.3%, respectively. Significant risk factors were cattle contact, high goat density near the farm, sheep supply from two provinces, high frequency of refreshing stable bedding, farm started before 1990 and presence of the Blessumer breed.

Conclusions
Coxiella burnetii infection is common among sheep farm residents. In non-dairy sheep farm residents, most risk factors indicate current or past goat and cattle exposure, with limited factors involving sheep. Sub-typing human, cattle, goat, and sheep Coxiella burnetii strains might elucidate their relative role in the infection risk of sheep farm residents.

Published: 06 Jun, 2013

 
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