For citation purposes: Fox CH, Neuhaus K, Vassalotti JA. Importance of urine albumin?creatinine ratio in the diagnosis and prognosis of chronic kidney disease. OA Nephrology 2013 Nov 01;1(3):21.



Importance of urine albumin–creatinine ratio in the diagnosis and prognosis of chronic kidney disease

CH Fox, K Neuhaus, JA Vassalotti

Authors affiliations

(1) University at Buffalo , School of Medicine and Biomedical Sciences, Buffalo, NY 14203, USA

(2) University of Kansas School of Medicine , Kansas City, KS 66160, USA

(3) Mount Sinai Medical Center, National Kidney Foundation, Inc., New York, NY 10016, USA

* Corresponding author Email:



New Kidney Disease Improving Global Outcomes guidelines represent a significant change from the National Kidney Foundation’s Kidney Disease Outcomes Quality Initiative, which indicate that the urinary albumin/creatinine ratio is now integral to the classification of chronic kidney disease. The urinary albumin/creatinine ratio has been found to be fundamentally important for both the diagnosis and the prognosis of chronic kidney disease. It is now recommended that all patients with diabetes or hypertension be screened annually with this test. The presence of albuminuria helps decide the medications for the treatment of hypertension. This review discusses the importance of urine albumin–creatinine ratio in chronic kidney disease.


More research is needed to determine definitively whether or not the treatment of albuminuria delays the progression of chronic kidney disease and reduces mortality.

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