(1) University of Ferrara, Ferrara, ITALY
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Injectable poly-L-lactic acid is a biodegradable compound that has been widely used for the last 30 years throughout Europe and the USA in a wide range of medical devices. It is a soft tissue filler most commonly used to restore volume of depressed areas of the midface or temporal fossa by stimulating neocollagenesis, increasing dermal thickness, and enhancing volume.
The aim of this review is to present an update on the uses, the techniques and the adverse events of poly-L-lactic acid filler in facial volume restoration.
The mechanism of action of poly-L-lactic acid requires techniques and patient management as incorrect injection technique can cause device-related adverse events by overstimulation of the fibroblasts.