For citation purposes: Ulu-Kilic A, Ahmed SS, Alp E, Doğanay M. Challenge of intensive care unit-acquired infections and Acinetobacter baumannii in developing countries. OA Critical Care 2013 Mar 01;1(1):2.

Critical review

Critical Care Medicine & Pain

Challenge of intensive care unit-acquired infections and in developing countries

A Ulu-Kilic, SS Ahmed, E Alp, M Doğanay*

Authors affiliations

Department of Infectious Disease, Faculty of Medicine, Erciyes University, 38039-Kayseri/Turkey

* Corresponding author Email:



The burden of antibiotic usage is also very high in intensive care units. Nosocomial intensive care unit-acquired infections and antimicrobial resistance are global problems, and many epidemiological studies are carried out, especially from developed countries. However, available data of patient population and characteristics of intensive care units are very limited in developing countries. The prevalence of infection and mortality rates are higher in countries with limited resources associated with the quality of care. Infection control strategies such as hand hygiene, rational antibiotic utilisation, continuous education and performance feedback demonstrated a significant reduction in the infection rates in these countries. Acinetobacter baumannii is common cause of nosocomial infections worldwide. In recent years, interest in infections caused by A. baumannii has gradually increased, and current studies indicate that this pathogen is more resistant and virulent, becoming a serious nosocomial threat. This critical review discusses the prevalence of A. baumannii and other intensive care unit-acquired infections in developing countries.


Intensive care unit-acquired infections caused by resistant organisms, prominently A. baumannii, are a global challenge. Large scale studies of intensive care unit-acquired infections in developing countries and guidelines including globally applicable infection control strategies to reduce these infections are essential.

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