For citation purposes: Ivanov SY, Mukhametshin RF, Muraev AA, Solodkaya DV. Synthetic materials used for the substitution of bone defects: Critical review. Annals of Oral & Maxillofacial Surgery 2013 Feb 01;1(1):4.

Critical review


Synthetic materials used for the substitution of bone defects

SY Ivanov, RF Mukhametshin, AA Muraev, DV Solodkaya

Authors affiliations

GBOU VPO ‘Nizhny Novgorod State Medical Academy’, Health Ministry of Russia, Nizhny Novgorod, Russia (603005, Nizhny Novgorod, Faculty of Dentistry FPKV, Square of Minina and Pozharskogo, 10/1, Russia)

* Corresponding author Email:



The need for bone substitution materials has been increased due to teeth loss, trauma, tumour and bone reconstructive surgery. Various types of bone grafts have been developed to repair craniofacial bone defects over many years. Here, an analysis of Russian and foreign sources of literature, reflecting the characteristics of synthetic bone graft materials used in modern dental practice to fill bone defects, has been done. The importance of developing a new generation of synthetic material to replace bone defects is emphasized. The aim of this critical review is to discuss the synthetic materials that can be used as a substitute for bone defects.


New materials will allow bone tissue regeneration and defect reconstruction. We call on more research into this topic to increase our understanding and improve materials we currently use or discover a better suited material.

Licensee OA Publishing London 2013. Creative Commons Attribution License (CC-BY)