(1) Department of Pathology, Biological Sciences Institute, School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais – Brazil.
(2) Department of Oral Pathology, School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais – Brazil.
* Corresponding author Email: firstname.lastname@example.org
Molecular changes in oral leukoplakia (OL) or in adjacent ‘clinically normal mucosa’ might influence the persistence/recurrence of OL, allowing an opportunity for transformation into squamous cell carcinoma.
Clinicians must understand that available treatment options are limited in their capacity to prevent oral cancer.
Surgical resection is still currently the best technique for management of OL. Patients with OL also need to adjust their lifestyle.
We call for further studies to improve our understanding.