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Myectomy – How Does It Work? Risks And Benefits

The septal myectomy is open-heart surgery. It is used to treat hypertrophic cardiomyopathy, a thickened heart muscle. Your physician will remove a section of thickened heart tissue during surgery to enhance blood flow through the heart. In most cases, septal myectomy effectively cures hypertrophic cardiomyopathy.

What Is Myectomy?

This is a surgical procedure that removes the thicker heart wall. It is utilized when drugs no longer control the symptoms of hypertrophic cardiomyopathy.

It is quite helpful in symptom relief and enhancing quality of life. In reality, myectomy is likely to prolong life: in one published research, 95 percent of patients who had surgery were still living 10 years later, but only 73 percent of people with comparable symptoms who did not have surgery were still alive.

Although the surgery is technically tricky, Stanford surgeons were the first to do it and have completed hundreds of surgeries since 1972.

Who Should Undergo Myectomy

Patients with obstructive hypertrophic cardiomyopathy are advised to have a myectomy, especially if they have attempted other treatment options but have not found relief and if they have a considerable blockage that significantly inhibits blood flow from the left ventricle to the aorta.

For a definite diagnosis, all patients being evaluated for myectomy must have a comprehensive echocardiography, cardiac catheterization, and other regular diagnostics.

The surgery may be performed on elderly individuals, but if the dangers exceed the potential advantages.

Myectomy, which involves hospitalization, has a high percentage of success, with patients receiving rapid relief from blockage and other symptoms. There have also been reports of considerable improvements in their quality of life due to myectomy.

Myectomy Procedure

The patient is put under general anesthetic at the outset of the operation. To reach the heart, the surgeon creates a wide incision in the chest and splits the breastbone. A tiny cannula tube is passed into the aorta and the aortic valve. The insertion of a cannula eliminates the need for the surgeon to create an incision in the heart. After that, the pressure gradients between the aorta and the left ventricle are measured. Optical imaging technologies, such as echocardiograms, advise the surgeon during the process. The use of a heart-lung or bypass machine momentarily suspends cardiac function. The thickened muscles are then recognized and placed. The surgeon eliminates these muscle tissues that create a blockage and reduces blood flow using specialized instruments.

The patient is removed from the bypass machine after removing the thicker tissues surgeon checks the pressure gradient once again to ensure that blood flow has improved. Pacing wires and drain tubes are temporarily inserted into the chest. Sutures are used to seal the incision and rewire the breastbone.

Patients are immediately put in critical care and monitored, and may be equipped with an implantable cardioverter-defibrillator to prevent any aberrant cardiac rhythms. After two months, most patients recover and may resume regular activities. They are encouraged to maintain a healthy lifestyle after surgery to aid recovery and prevent long-term consequences. An appropriate rehabilitation program is also required, although intense physical activity is prohibited.

Human heart model
Human heart model

Risks Of Myectomy

Complications are uncommon after myomectomy. Nonetheless, the technique presents a distinct set of obstacles. Myomectomy has the following risks:

  • Excessive bleeding: Many women with uterine leiomyomas already have low blood counts (anemia) due to excessive monthly bleeding, putting them at a greater risk of complications from blood loss. Your doctor may advise you to increase your blood count before surgery. Surgeons take great precautions to prevent excessive bleeding during myomectomy. These may involve employing tourniquets and clamps to stop blood flow from the uterine arteries and injecting drugs around fibroids to induce blood vessels to constrict. Most actions, however, do not lessen the likelihood of requiring a transfusion. In general, research shows that hysterectomy causes less blood loss than myomectomy for uteruses of comparable size.
  • The scar tissue: Incisions into the uterus to remove fibroids may result in adhesions, which are bands of scar tissue that form following surgery. Laparoscopic myomectomy, as opposed to abdominal myomectomy, may result in fewer adhesions (laparotomy).
  • Complications during pregnancy or delivery: If you get pregnant, a myomectomy may raise some risks during delivery. Suppose your surgeon has to create a large incision in your uterine wall. In that case, the doctor who supervises your future pregnancy may advise a C-section to prevent uterine rupture during birth, an extremely uncommon pregnancy problem. Fibroids have also been linked to pregnancy problems.
  • A hysterectomy is a rare possibility. If the bleeding is unmanageable or abnormalities are discovered in addition to the fibroids, the surgeon may have to remove the uterus.
  • It is doubtful that a malignant tumor would spread. A malignant tumor may sometimes be misdiagnosed as a fibroid. Taking out cancer, especially if it's broken into little pieces (morcellation) to remove through a small incision, can lead to the spread of cancer. This is more likely to happen after menopause and as women age.

The Food and Drug Administration (FDA) advised against using a laparoscopic power morcellator for most women having myomectomy in 2014. The American College of Obstetricians and Gynecologists (ACOG) recommends you talk to your surgeon about the risks and benefits of morcellation.

How To Prevent Complications During Myectomy

Your doctor may advise you to undertake the following to reduce the risks of myomectomy surgery:

  • Vitamins and iron supplements: If you have iron-deficiency anemia due to heavy menstrual cycles, your doctor may advise you to take iron supplements and vitamins to boost your blood count before surgery.
  • Hormonal therapy: Hormonal therapy b surgery is another option for treating anemia. To halt or reduce your menstrual flow, your doctor may prescribe a gonadotropin-releasing hormone (GnRH) agonist, birth control tablets, or other hormonal therapy. When used as treatment, a GnRH agonist inhibits the synthesis of estrogen and progesterone, preventing menstruation and enabling you to replenish hemoglobin and iron reserves.
  • Fibroid shrinkage therapy: Some hormonal therapies, such as GnRH agonist therapy, can also shrink your fibroids and uterus sufficiently to allow your surgeon to use a less invasive surgical approach, such as a smaller, horizontal incision rather than a vertical incision or a laparoscopic procedure rather than an open procedure.

According to some studies, intermittent GnRH agonist medication may shrink fibroids and reduce bleeding to the point where surgery is not required.

In most women, GnRH agonist treatment induces menopausal symptoms such as hot flashes, nocturnal sweats, and vaginal dryness. However, these side effects disappear as you stop using the drug. Treatment usually lasts many months before surgery.

Evidence shows that not all women should have GnRH agonist treatment before myomectomy. GnRH agonist treatment may soften and reduce fibroids to the point that they are more difficult to detect. The medication's cost and the danger of adverse effects must be evaluated against the advantages.

Another class of medications known as selective progesterone receptor modulators (SPRMs), including ulipristal (ella), may shrink fibroids and decrease bleeding. Ulipristal is allowed for three months of treatment prior to a myomectomy outside of the United States.

People Also Ask

How Long Does It Take To Recover From A Myectomy?

It also relies on whether or not there are any issues. Complete recovery before returning to regular activities after an open myomectomy might take up to six weeks. After a laparoscopic myomectomy, you may remain in the hospital overnight before returning home. Home recovery takes two to four weeks.

What Is A Myomectomy Of The Heart?

A septal myectomy is an open-heart treatment in which a portion of the thicker, overgrown septum between the ventricles is removed, as depicted in the heart on the right.

How Is A Myectomy Performed?

Your surgeon will cut an incision through the center of your chest and detach a portion of your breastbone. The surgeons will connect you to a heart-lung machine. This machine will give oxygen to your blood during your procedure and pump it to your body. Your surgeon will remove a section of your thickened septum.

What Is A Myectomy In Medical Terms?

Myectomy is the surgical treatment for hypertrophic cardiomyopathy. It entails removing a section of the septal wall that has swollen, resulting in restricted blood flow from the left ventricle to the aorta.


The septal myectomy is open-heart surgery. These procedures are complicated and need many weeks of recuperation time. While a septal myectomy is major surgery, it is a very successful therapy for hypertrophic cardiomyopathy.

Septal myectomies are quite successful. In one research, 94 percent of individuals reported symptom relief after surgery. People who underwent a septal myectomy had the same long-term survival rates as the general population.

About The Authors

Suleman Shah

Suleman Shah - Suleman Shah is a researcher and freelance writer. As a researcher, he has worked with MNS University of Agriculture, Multan (Pakistan) and Texas A & M University (USA). He regularly writes science articles and blogs for science news website immersse.com and open access publishers OA Publishing London and Scientific Times. He loves to keep himself updated on scientific developments and convert these developments into everyday language to update the readers about the developments in the scientific era. His primary research focus is Plant sciences, and he contributed to this field by publishing his research in scientific journals and presenting his work at many Conferences. Shah graduated from the University of Agriculture Faisalabad (Pakistan) and started his professional carrier with Jaffer Agro Services and later with the Agriculture Department of the Government of Pakistan. His research interest compelled and attracted him to proceed with his carrier in Plant sciences research. So, he started his Ph.D. in Soil Science at MNS University of Agriculture Multan (Pakistan). Later, he started working as a visiting scholar with Texas A&M University (USA). Shah’s experience with big Open Excess publishers like Springers, Frontiers, MDPI, etc., testified to his belief in Open Access as a barrier-removing mechanism between researchers and the readers of their research. Shah believes that Open Access is revolutionizing the publication process and benefitting research in all fields.

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