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Using CBD For Pain - The Best Ways, Dosage & Delivery

Using CBD for pain management has been accepted in all of the world's main historic civilizations, from Asia to the Middle East, Europe, and the Americas. Cannabis has been proven to be an efficient and safe analgesic for a variety of pains by scientific research over the last many decades. Pain is the most common cause for which individuals use CBD today.

For the relief of certain kinds of pain, I believe, there is no more useful medicine than Cannabis within our reach,” wrote Sir John Russell Reynolds, neurologist, epilepsy research pioneer, and physician to Queen Victoria back in 1859.

Cannabis in general falls into this category. Over seventy million people in the United States suffer from chronic pain, which is defined as discomfort that lasts for more than a hundred days per year. Most neuropathic and many nociceptive types of pain are treated with cannabis. The endocannabinoid system is implicated in the cerebral and peripheral processing of pain signals, according to several studies. The majority of CBD pain treatment conversations emphasize the need of determining the appropriate dosage.

Cannabinoids can be used in conjuction with opioid drugs, and research has shown that they can lower the quantity of opioids required, reduce tolerance, and alleviate withdrawal symptoms. Cannabinoids have been shown to be effective for various types of neuropathic pain in at least 10 randomized, controlled trials involving over 1,000 patients.

A Caucasian woman wearing a white sleeveless t-shirt and a blue jean short holding her back with one hand in pain
A Caucasian woman wearing a white sleeveless t-shirt and a blue jean short holding her back with one hand in pain

What Is The Endocannabinoid System?

Rather with merely CBD, most pain studies have used a combination of cannabinoids, such as THC or a combination of many. The cannabis plant contains approximately 100 distinct cannabinoids, each with its own set of properties and effects. Apart from CBD, tetrahydrocannabinol (THC) is a well-known cannabinoid that can provide a "high." The ECS, a cell-signaling system found in all mammals, interacts with all cannabinoids.

The ECS is in charge of regulating and balancing bodily functions that affect our mood, sleep, immune system, and metabolism. Endocannabinoids, which are cannabinoids produced naturally, and cannabinoid receptors, which are found throughout the brain and nervous system, make up the ECS. CBD and other cannabinoids interact with these receptors and activate systems in the brain that change how it interprets pain.

What Types Of Pain Does CBD Work For?

Individuals can experience several types of pain due to the complexity of the underlying causes and symptoms of pain.

Chronic Pain

Chronic pain is defined as persistent pain that persists for more than a few months after an accident or sickness has healed. Back discomfort and recurrent headaches are two examples of chronic pain. While patients can manage chronic pain with acupuncture, medicine, and surgery, severe chronic pain cannot be healed and must be monitored and managed for the rest of one's life.

Because chronic pain is a long-term condition, some patients are turning to natural and alternative therapy options rather than traditional medications, which are frequently accompanied with negative side effects. CBD oil is still a popular choice because studies have shown that it has beneficial effects on chronic pain.

Neuropathic Pain

Nerve irritation owing to injury causes neuropathic pain. It causes shooting or scorching sensations, and the affected areas are particularly sensitive to touch. Pins and needles, agonizing pain levels, and difficulties recognizing numbness or changes in temperature are all indications of neuropathic pain, which damages the somatosensory nerve system.

Neuropathic pain has several causes and treatments. Alcoholism, toxicity exposure, and nutritional abnormalities are some of the reasons that cause neuropathic pain. The severity of the pain will also influence the treatment. Antidepressants and nonsteroidal anti-inflammatory medicines (NSAIDs) are two types of medications that can assist relieve pain in patients. Many others, on the other hand, will require stronger painkillers and will combine natural pain relievers, such as CBD oil, with their regular medications.

A woman wearing a blue sleeveless t-shirt holding her belly with both hands in pain
A woman wearing a blue sleeveless t-shirt holding her belly with both hands in pain

Cancer Treatment Pain

Dealing with the myriad side effects of cancer therapies is one of the most difficult stages for those with the disease. Hormone therapy, immunotherapy, and chemotherapy are examples of popular cancer treatment choices. Pain, vomiting, nausea, and loss of appetite are all possible side effects of these therapy.

Pain is common among cancer patients. CBD oil and oral sprays have shown to be effective in the treatment of cancer pain. CBD oil has been studied for its role in lowering inflammation and overall discomfort associated with illnesses such as cancer.

CBD Oil And Inflammation

Inflammation and pain are mutually exclusive. Inflammatory pain is caused by an abnormal immune system response, which is linked to diseases such as arthritis. CBD has showed potential in decreasing inflammation in the neurological system and brain. This could help people with persistent pain and sleep problems, which can lead to sleeplessness and immune system responses.

What Are The Side Effects Of Pain?

Pain is complicated, and it is generated by a variety of elements that frequently interact to send signals to the brain. Pain is often caused by a specific injury or health condition, but in some cases, the underlying causes are less visible or unclear, necessitating several testing. Whatever the reason, pain can be extremely debilitating, resulting in other illnesses or side effects that are frequently disregarded.

The following are some common pain-related side effects:

  • Decreased sleep quality.
  • Depression and anxiety.
  • Changes in appetite.
  • Decreased mood.

Our emotional and physical well-being are inextricably linked. People who experience a lot of pain are more prone to despair and anxiety. Chronic pain can also cause poor sleep quality or even insomnia since the pain stops the patient from getting a good night's sleep. All of these adverse effects have the potential to escalate out of control, creating a pain feedback loop.

A bunch of cannabis sativa leaves
A bunch of cannabis sativa leaves

How Do I Use CBD For Pain?

Patients should collaborate with a health care provider that has experience suggesting CBD or medicinal cannabis to establish and fine-tune dosage and delivery strategies for them. At the same time, well-informed patients can act as their own health consultants.

Oral CBD products with a 20:1 or greater CBD:THC ratio, delivered as drops, pills, or sweets, can be quite useful in relieving pain, particularly inflammatory pain. The majority of CBD pain treatment conversations emphasize the need of determining the appropriate dosage. Always begin with a microdose to determine sensitivity, then gradually increase your dosage within the dosing range based on your body weight until symptoms disappear. To treat pain, the micro to standard dose is usually recommended, but patients should closely monitor their condition and experiment to find the right formula; 10–40 mg of CBD or CBD+THC combined is usually sufficient.

If CBD-dominant products aren't adequate to help with a certain problem, products with a higher THC ratio may be prescribed. Sativa types with higher myrcene contents could be added to the formula for daytime use. Indica strains are preferred for pain relief in general, and especially at night and in the evening. If you've never used THC before, proceed with caution and gradually increase your dosage.

The most effective CBD:THC ratio for both neuropathic and inflammatory pain, according to research and patient input, is 4:1 CBD:THC. However, each person is different—some people prefer a 1:1 CBD:THC ratio, while others prefer a high-THC strain if they can tolerate it. Each patient's tolerance and sensitivity will vary, therefore titration will be necessary to determine the best strain and ratio combination.

CBC, CBG, THCV, and THCA are all cannabinoids that have been found to reduce pain. Chemotypes strong in beta-caryophyllene, myrcene, and linalool provide significant pain relief while also enhancing the analgesic effects of other cannabinoids.

Vaporizing or smoking are effective for relieving immediate symptoms, such as discomfort. Most ingested products take thirty to sixty minutes to take action (faster on an empty stomach) and last six to eight hours, whereas medicine has an instant impact that lasts one to three hours. Vaporizers with a CO2 concentrate cartridge are quite effective, and they come in a variety of CBD to THC ratios. Herbal vaporizers that employ the entire plant are another good option. In comparison to inhaled medications, sublingual sprays or tinctures administered as liquid drops have a faster onset and last longer.

Topical medications can be used to treat localized pain. CBD-dominant cannabis and THC strains can both be used to make these. Topicals have an effect on cells around the application site and through multiple layers of tissue, but they do not cross the blood-brain barrier, hence they are not psychoactive.

These can come in a variety of forms, including oils, ointments, salves, and other products, with different CBD and THC ratios (a ratio of 1:1 is often recommended as ideal for skin application). CB2 receptors are found in the greatest number and concentration in the skin.


CBD doesn't make you high, but it can help you relax if you take enough (which is usually determined by your weight). Drowsiness, nausea, and exhaustion are the most common side effects. It is unlikely to have a negative effect on your mood or cognitive abilities, making it a safer and preferable product for many.

While there isn't enough data to recommend treating pain using CBD, researchers believe it has a lot of potential.

CBD is generally well tolerated; nevertheless, before using it for the first time, people should always consult with a health practitioner.

People Ask

Does CBD Help Against Pain?

CBD acts on a number of biological processes in the body, which may assist to relieve pain. CBD is an anti-inflammatory, antioxidant, and analgesic. CBD may also help patients who suffer from chronic pain feel less anxious.

Is CBD Fast Acting For Pain?

The speed with which CBD relieves pain depends on a variety of factors, including the underlying health condition, CBD product, and dosage. According to the American Arthritis Foundation, a CBD spray or tincture may take 15–45 minutes to take effect.

Is CBD Good For Inflammation?

When CBD is administered to the skin, according to one animal study published in the European Journal of Pain, it can help reduce pain and inflammation caused by arthritis. CBD has also been shown to reduce inflammatory and neuropathic pain, two types of pain that are difficult to treat.

Does CBD Heal Or Just Mask Pain?

CBD, on the other hand, isn't merely a brain-receptor tinker. It has anti-inflammatory qualities, so rather than disguising your discomfort, it addresses the source of the problem. Yes, you may feel better before fully recovering, but CBD also aids in the healing process.

About The Authors

Suleman Shah

Suleman Shah - Suleman Shah is a researcher and freelance writer. As a researcher, he has worked with MNS University of Agriculture, Multan (Pakistan) and Texas A & M University (USA). He regularly writes science articles and blogs for science news website immersse.com and open access publishers OA Publishing London and Scientific Times. He loves to keep himself updated on scientific developments and convert these developments into everyday language to update the readers about the developments in the scientific era. His primary research focus is Plant sciences, and he contributed to this field by publishing his research in scientific journals and presenting his work at many Conferences. Shah graduated from the University of Agriculture Faisalabad (Pakistan) and started his professional carrier with Jaffer Agro Services and later with the Agriculture Department of the Government of Pakistan. His research interest compelled and attracted him to proceed with his carrier in Plant sciences research. So, he started his Ph.D. in Soil Science at MNS University of Agriculture Multan (Pakistan). Later, he started working as a visiting scholar with Texas A&M University (USA). Shah’s experience with big Open Excess publishers like Springers, Frontiers, MDPI, etc., testified to his belief in Open Access as a barrier-removing mechanism between researchers and the readers of their research. Shah believes that Open Access is revolutionizing the publication process and benefitting research in all fields.

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